Yale Gerstein Lab

Analysis of occurrences of PROSITE patterns in the Intergenic region

We analyzed the occurrences of conserved protein patterns in the intergenic region of yeast, worm, fruitfly and human chromosomes 21 and 22. We found that 67 pseudomotif p atterns are over-represented in the fly genome, and 34, in the worm. Among the over-represented patterns are the well-known Zinc finger, leucine zipper, and nucleotide-bin ding motif. We argue that the enrichment of these patterns in the intergenic region reflects the fact that some of them are remaining fragments of ancient disabled protein -coding genes.

Here is an interactive table, which contains data for all four species: yeast, worm, fruit fly, and human chromosome 21 & 22.

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