Using the recently identified human ribosomal protein (RP) pseudogene sequences, we have thoroughly
studied DNA mutation patterns in the human genome. Overall, we found that nucleotide transitions are
more common than transversions, by roughly a factor of two. Moreover, the substitution rates amongst
the 12 possible nucleotide pairs are not homogeneous as they are affected by the type of immediately
neighboring nucleotides and the overall local G+C content. We also found that deletions are about
three times more common than insertions.